When childhood friends Yui and Naoki are by chance reunited as adults, they begin to feel they were destined for each other. However, just as Naoki prepares to propose to Yui, he becomes embroiled in a mysterious incident and dies.
Now Naoki's soul wanders the world unable to express his true feelings for Yui. Yuzuru, a detective and the only person who can see Naoki, goes in pursuit of the truth behind Naoki’s death. At Naoki tries to use Yuzuru to talk to Yui, but will he be able to convey his message of love?

Tokyo 2023. Japan’s prime minister announces a plan to store contaminated material in deep-sea strata while entrusting a team of young technocrats to protect Japan’s future. Meanwhile, the public is alarmed by sensational magazine articles predicting the sinking of the Kanto plain owing to the disappearance of an island off the Izu coast. With demonstrators in the streets, a young government official Amami tries to restore order just as a corruption scandal linking the government to a profitable eco-business firm erupts. When Amami and a government colleague escape for a scuba diving trip, they encounter an earth-shattering event.

Political circumstances force upstart doctor, Kazuaki Okita, to leave a busy hospital life and his girlfriend behind and go to the United States where he takes part in countless operations and develops into a top-notch surgeon. Then, at the behest of his ex-lover’s father, he returns to Japan to find his girlfriend has gone and married his best friend who actually masterminded Okita’s original exile from the hospital ten years ago. Unbeknownst to all of this, Okita is reunited with his ex-lover and best friend and the varying peculiarities of the hospital staff. Though awkward at times, Okita is single-minded in his pursuit of good medicine, endearing him to his patients and forcing his colleagues to rethink the true meaning of medicine and the value of life in a hospital drama swirling with passion, ambition, friendship, jealousy and pride.

99 years ago, a Japanese man emigrated to the vast expanse of America with hopes of survival and dreams of a brighter future. He and those like him were settlers, 1st generation Japanese-Americans. From them were issued a second generation which grew up bearing little knowledge of, nor devotion to, their parents’ homeland. And yet fate was to deliver them all a cruel blow... as war proceeded to tear them apart along national and generational lines. This is a story about Japanese immigrants who endured the horrors and tragedy of war, overcame deep prejudice and attained their dreams in a new land through love and courage.

The eponymous dual heroines are 20-year old NANA Osaki and Nana Komatsu. Strong and independent, NANA comes from a dysfunctional background and is the vocalist of a punk band looking to find a major record deal. On the other hand, naive and sweet-natured Nana has been blessed with a stable family environment and the most pressing issue in her life is her boyfriend! Fate brings these two very different girls together and the film traces their fortunes as they navigate the trials and tribulations of love and the difficulties facing young women in the bustling and often intimidating metropolis of Tokyo.